FORT WORTH, Texas, February 26, 2025 – Alcon (SIX/NYSE: ALC), the global leader in eye care dedicated to helping people see brilliantly, today unveiled its robust line-up of announcements and updates for the 2025 SECO International meeting in Atlanta, Georgia. Alcon is highlighting the full commercial availability of PRECISION7^® sphere and toric, as well as debuting its latest advancement in the treatment of dry eye. Additionally, the company is showcasing its expanded patient engagement tools for allergy sufferers with MARLO, including OTC Pataday^® availability.

“Alcon’s presence at this year’s SECO International represents our steadfast commitment to bringing the latest innovations and digital resources to address the needs of today’s patients and Eye Care Professionals,” said Kristen Brotherson, General Manager, U.S. Vision Care, Alcon. “We are proud to highlight data from our investigational dry eye product, debut new innovations across contact lenses and ocular health—including updated MARLO features—as we continue to advance treatment options and resources for everyone.”

PRECISION7 sphere and toric join Alcon’s WaterInnovations contact lens portfolio, expanding the power of water to more patients 
PRECISION7—the lens that delivers breakthrough performance and an easy-to-remember replacement schedule closer to the daily lenses that eye care professionals prefer^**—is now fully commercially available to all eye care professionals in the U.S.^1,2 The lens is the latest addition to the Alcon WaterInnovations™ portfolio, ECPs preferred choice for all day comfort.³

Made of serafilcon A, a new SiHy material, PRECISION7’s breakthrough ACTIV-FLO^® System is a unique combination of a water-loving moisturizing agent embedded in the lens matrix and a proprietary replenishing agent that is continuously released to moisturize the surface over seven days.^4-6 More information about PRECISION7 will be available at the Alcon booth.

Alcon to showcase the latest addition to the SYSTANE portfolio, SYSTANE PRO PF 
Developed exclusively to offer dry eye symptom relief, SYSTANE^® PRO Preservative-Free (PF) is a one-of-a-kind, triple-action formula that provides sustained hydration, restores tear film stability, and protects against further irritation of dry eyes.^7,8 With active ingredient propylene glycol, hyaluronate  supports the eyes’ pH balance, delivering long-lasting dry eye symptom relief for all major types of dry eyes, which affects an estimated 45.5 million patients in the United States.^8-10 

New Phase 3 clinical study results presented for AR-15512 (Acoltremon 0.003%), a potential new pharmaceutical treatment option for DED^11,* 
Investigators Selina R. McGee, OD, FAAO, and Cory Lappin, OD, MS, FAAO will present Ocular Surface Staining Reductions With Acoltremon 0.003%: Results From Phase 3 Pivotal Clinical Studies (COMET-2 and COMET-3) at a networking breakfast on Thursday, February 27 at the Omni Atlanta Hotel at Centennial Park (190 Marietta St NW, Atlanta, GA 30303) from 6:30 AM-7:45 AM ET.

Acoltremon 0.003% is Alcon’s pharmaceutical dry eye pipeline candidate and a potent, first-in-class transient receptor potential melastatin 8 (TRPM8) agonist.^11,*  

MARLO latest enhancements center on fostering patient engagement with OTC products availability and added resource for allergy sufferers 

At SECO 2025, MARLO - Alcon’s digital solution - is celebrating five years of continuous innovation within the platform. Alcon will showcase MARLO’s expanded digital tools and highlight its latest features, including:

• MARLO remains Alcon's one-stop solution for ordering contact lenses, contact lens care products, including OPTI-FREE^® and CLEAR CARE^®, and Alcon OTC products from Pataday and SYSTANE (available with contact lens order). COMING SOON: our latest innovation in dry eye relief, SYSTANE PRO PF.
• On the MARLO App, patients can now opt in for push notifications alerting them to high local allergen levels.^† This new feature is designed to help more patients understand their exposure to allergens and easily access available OTC solutions on a single platform.

Alcon unveils new digital Spanish language Pataday resources for allergy sufferers 
As part of these allergy resource enhancements, Alcon is also showcasing new English and Spanish language resources available on Pataday.com to help ECPs better communicate key information about Pataday to their patients with allergies.

More on each of these announcements, including samples, demonstrations and literature, will be available at Alcon Booth #235 from February 26 – March 2, 2025.

About Alcon

Alcon helps people see brilliantly. As the global leader in eye care with a heritage spanning over 75 years, we offer the broadest portfolio of products to enhance sight and improve people’s lives. Our Surgical and Vision Care products touch the lives of more than 260 million people in over 140 countries each year living with conditions like cataracts, glaucoma, retinal diseases and refractive errors. Our more than 25,000 associates are enhancing the quality of life through innovative products, partnerships with Eye Care Professionals and programs that advance access to quality eye care. Learn more at www.alcon.com.

Important Safety Information for Precision7^® (serafilcon A) contact lenses:

For daily wear or extended wear up to 6 nights for near/far-sightedness. Risk of serious eye problems (i.e., corneal ulcer) is greater for extended wear. In rare cases, loss of vision may result. Side effects like discomfort, mild burning or stinging may occur. See product instructions for complete wear, care and safety information. Rx Only.

*AR-15512 is an investigational drug product that has been filed with the U.S. Food and Drug Administration (FDA) for approval; it is not yet approved.

**Based on agreement with the statement "I believe daily disposable lenses are better for my patients overall.” 
†Push notifications are for iOS only. Android coming soon.

References

1. In a 2-week prospective clinical study in the US; n=181; CLEAR CARE^® Cleaning & Disinfecting Solution used for cleaning and disinfection; Alcon data on file, 2023. 
2. Based on a survey of 500 US optometrists who fit contact lenses; Alcon data on file, 2023.
3. Alcon Data on File, 2025. 
4. Zheng Y, Dou J, Wang Y, et al. Sustained release of a polymeric wetting agent from a silicone-hydrogel contact lens material. ACS Omega. 2022;7(33):29223-29230. doi: 10.1021/acsomega.2c03310. 
5. Phan CM, Chan VWY, Drolle E, et al. Evaluating the in vitro wettability and coefficient of friction of a novel and contemporary reusable silicone hydrogel contact lens materials using an in vitro blink model. Cont Lens Anterior Eye. 2024; Volume 47(2):1-11. 
6. PRECISION7^® Instructions for Use. 
7. Systane^® PRO PF Label.
8. Alcon data on file, 2025.
9. Alcon data on file, 2024.
10. Dry Eye Products Markets Report, Market Scope, 2023.
11. McGee S, Evans D, et al. Ocular Surface Staining Reductions with Acoltremon 0.003%: Results From Phase 3 Pivotal Clinical Studies (COMET-2 and COMET-3) SECO International. Atlanta. 2025.

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